Sleep Deprivation and an Under Active Thyroid

  • Tue 16th Apr 2019 - 11:06am
    The thyroid cells are protein-secreting cells and one  4 Day Thyroid Diet  of their major products is thyroglobulin. Thyroglobulin is a large glycoprotein molecule with a molecular weight of around 335,000. Each molecule of thyroglobulin contains around 70 amino acids called tyrosine, the major substrate that combines with iodine to form the thyroid hormones. Basically, the thyroid hormones are formed inside the thyroglobulin. The first essential step in the formation of thyroid hormone is the oxidation of iodide ions to nascent iodine capable of combining with tyrosine. This process is promoted by the enzyme peroxidase and its accompanying hydrogen peroxide. The next step is the organification of iodine or the binding of iodine with the thyroglobulin molecule. Even in its oxidized form, iodine binds quite slowly to tyrosine. In the thyroid cell, however, iodine is associated with aniodinase enzyme which speeds up the organification to a matter of seconds or minutes. Tyrosine is first iodized to monoiodotyrosine and then to diiodotyrosine. The iodotyrosine formed then couple with one another to form thyroid hormones. A coupling between monoiodotyrosine and diiodotyrosine yieldstriiodothyronine and a coupling between two molecules of diiodotyrosine will form thyroxine, which is the major hormonal product of the thyroid gland.

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